Santander is a department of Colombia. Santander inherited the name of one of the nine original states of the United States of Colombia. It is located in the central northern part of the country, borders the Magdalena River to the east, Boyacá to the south and southeast, the Norte de Santander Department to the northeast, the Cesar Department to th…Santander is a department of Colombia. Santander inherited the name of one of the nine original states of the United States of Colombia. It is located in the central northern part of the country, borders the Magdalena River to the east, Boyacá to the south and southeast, the Norte de Santander Department to the northeast, the Cesar Department to the north, the Bolivar and Antioquia Departments to the west. Its capital is the city of Bucaramanga.