Federal health officials say that not only has a Louisiana resident contracted the first severe case of bird flu in the U.S., but that the virus likely mutated in the patient. The findings raise concern regarding the adaptability of the virus.

A genetic analysis suggests the bird flu virus mutated inside a Louisiana patient who contracted the nation’s first severe case of the illness, the U.S. Centers for Disease Control and Prevention said this week.

Growing concerns surrounding the transmission of H5N1 bird flu. The CDC reports that samples collected from a severely ill patient in Louisiana showed signs of mutation, as they differ from the samples collected from sick and dead birds believed to have infected the man in the first place.