Grey’s Anatomy fans may be cheering the return of Jason George as Ben Warren after he spent seven seasons on spinoff Station 19. But the doctor that they get back may not exactly be the doctor that they remember.

"They had just started to figure out what their working relationship was when he went out to become a firefighter, but now he's coming in with a whole new level of confidence," George says of Ben and

Grey’s Anatomy couple Ben Warren and Miranda Bailey are back working together at Grey Sloan Memorial but not without its challenges, according to star Jason George.

Grey’s Anatomy couple Ben Warren and Miranda Bailey are back working together at Grey Sloan Memorial but not without its challenges, according to star Jason George. “She spent the last few years losing sleep over whether or not Ben was gonna make it home,

George tells PEOPLE that his return to 'Grey’s Anatomy' for season 21 has meant he gets to see "some of my favorite people every day"

While George is returning to very familiar territory in playing Dr. Ben Warren, there are still a lot of challenges (and joys!) in starting over.