Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how risks are assessed, and how potential treatments move from early discovery ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...

Tendinopathy is a common and significant clinical problem characterised by activity-related pain, focal tendon tenderness and intratendinous imaging changes. Recent histopathological studies have ...