B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

The body has an intricate system to defend against infections where each type of immune cell plays a distinct role. Now, a study led by researchers from the Penn State College of Medicine has ...

A new study reveals how Epstein–Barr virus reprogrammes B cells into autoimmune drivers, uncovering a direct mechanism linking EBV infection to lupus development.

Monoclonal B-cell lymphocytosis (MBL) is a condition in which a person has an excessive amount of abnormal B cells, which are a type of white blood cell known as lymphocytes. The number of abnormal B ...

Fenebrutinib shows promise as the first BTK inhibitor for both RMS and PPMS, reducing relapses and slowing disability progression. The FENhance 2 study demonstrated fenebrutinib's efficacy over ...

Diffuse large B cell lymphoma (DLBCL) is a cancer that affects white blood cells called B cell lymphocytes. Ordinarily, these cells help protect against infection and disease. In DLBCL, abnormalities ...