Tiny lab-grown models of human immune systems are helping researchers understand why cancer patients struggle to fight ...

“We're trying to target this pre-programmed subset of B cells,” Scharffenberger said. “If you're able to target them ...

The CAR-T cell therapy Aucatzyl was approved for relapsed or refractory B-cell precursor acute lymphoblastic leukemia based ...

However, patients can survive without B cells. With solid tumors ... immunosuppressive microenvironment that "can shut down ...

The FDA approved obecabtagene autoleucel for the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia.

Multiple players are exploring whether modalities designed to combat B cell malignancies can be repurposed against lupus, ...

When thinking about the immune system, most people think about B and T cells and how they can be trained to recognize ...

Positive CD3 expression allows for selection of T cells, CD19 for B-cells while CD14 and CD11b are used as inflammatory markers. Phenospace, an in-house ML image analyzing tool differentiates ...

Obe-cel was designed to increase T-cell persistence and reduce T-cell exhaustion and was shown to improve response rates and survival, particularly in patients with low leukemia burden.

Should you invest in Bicara Therapeutics Inc? Click for more on BCAX's promising cancer treatment, but proceed with caution ...