Medscape

FDA Changes Drug Trial Guidance: Experts Take Sides

The FDA has opened the door to the use of Bayesian statistical methods in clinical trials. The worry: Introducing ...
Clinical Trials Arena on MSN

The Bayesian challenge: complexity that pays off

The FDA has released draft guidance on how sponsors can use Bayesian models for clinical trials.
PharmExec

The Next Generation of Trial Designs: Supplementing Trials with Real-World Data

Real-world data (RWD) is transforming clinical research, augmenting existing randomized controlled trial (RCT) data to de-risk studies and improve generalizability. With regulators setting clearer ...
Morningstar

Professor Sarfaraz Niazi's Scientific Framework Adopted as FDA Modernizes Clinical Trial Evaluation Through Bayesian Methods

WASHINGTON, Jan. 20, 2026 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has issued new draft guidance modernizing statistical methodologies used in clinical trials, formally recognizing ...
ascopubs.org

Comparative Study of Bayesian Information Borrowing Methods in Oncology Clinical Trials

Cobimetinib Plus Vemurafenib in Patients With Colorectal Cancer With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study We divided the borrowing ...
ascopubs.org

Bayesian Approaches to Subgroup Analysis and Related Adaptive Clinical Trial Designs

We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...