Scientists have shown that a single injection of self-amplifying RNA, delivered into skeletal muscle rather than the heart itself, can trigger weeks of sustained hormone production that protects ...

After birth, the human heart loses its regenerative capacity almost completely. Damage to the heart muscle—for example, due to a heart attack—therefore usually leads to a permanent loss of function in ...

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...

Reduced progression of myocardial fibrosis measured by LGE on cardiac MRI (p=0.022)Significant improvement in LVEF versus placebo in patients ...

Tenaya’s Highly Selective HDAC6 Inhibitor TN-301 Outperformed Approved Pan-HDAC Inhibitor Givinostat in Improving Muscle Function and Correcting ...

Japanese researchers have transplanted human induced pluripotent stem cells (iPSCs) in a primate model of myocardial infarction and were able to restore heart muscle and function in monkeys. Developed ...

Cardiac complications in Duchenne muscular dystrophy (DMD) are the result of cardiac muscle involvement that accompanies the deterioration of skeletal muscle in the disease. The use of ...

Taylor has developed a high-speed imaging system called CAMERA (Computer-Assisted Measurements of Excitation-Response Activities), which allows him to record microscopic images of muscle cell ...