Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

Human cells have two copies of each chromosome, and this balance is essential for genes to be expressed in the appropriate ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

On the flipside, if telomeres are too long, it can also spell trouble because cancer cells require long telomeres to become longer lived, ‘immortal,’” says Mia Levine, associate professor of biology ...

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

For sexual reproduction to yield healthy offspring, newly generated oocytes—immature egg cells—must receive the correct amount of DNA after cell division. This process of segregating chromosomes ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

A metabolic enzyme also binds and unwinds RNA to promote translation of cell cycle genes. This dual role links energy status ...

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures ...