Varjosalo Lab's longstanding interest is the global and comprehensive understanding of how key cellular signaling molecules; protein kinases, protein phosphatases and transcription factors mediate ...

Epigenetic, bioelectromic, synaptic, and senolytic interventions could rejuvenate cells and counter the effects of aging.

Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to ...

The nervous system is comprised of two primary cell types: neurons and glial cells ... One interesting question is: Does neuregulin-ErbB signaling regulate CNS myelination as well?

In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...

How have immunohistochemistry and immunofluorescence been adapted to fit the growing needs of the life science research ...

Our goal is to uncover the circuits, cell types and pathways in which these disease-associated ... studies with Gabriel Nunez in the Department of Molecular and Cellular Pathology. During this period, ...

Analyzing these signaling responses at single-cell resolution has been difficult ... and changes in tissue organization ...

Our faculty participate actively in innovative research. Projects span from natural killer cell function, to tumor suppression by bitter melon, to participation in national liver pathology study ...

Katerina Politi, a professor of pathology who co-leads the Cancer Signaling Networks Research Program at the ... and uncovering the links between resistance, cancer cell plasticity, the tumor ...

We have studied the oncogenic role of the FAM83 proteins in a variety of cancers and are continuing to define the molecular interactions between the FAM83 proteins and EGFR/RAS signaling effectors, ...