Aim: To demonstrate the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. To achieve real-time process control by establishing automated regulation of ...

Anything that you do well is worth doing better over time. The term "continuous improvement" describes a process practiced by quality engineers but it speaks to something that every conscientious ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...

The benefits of continuous manufacturing a clear: increased output at lower cost with less waste. At least on paper, but 24/7 production can be a challenge for traditional drug firms says the team ...

Advances in process analytical technology have been achieved, but significant challenges remain. Continuous API manufacturing has the potential to provide tremendous benefits to the pharmaceutical ...

Advances in equipment, instrument, and control systems are enabling online monitoring of continuous API manufacturing. Continuous API manufacturing has the potential to provide tremendous benefits to ...

The extent to which products meet specifications needs to be systematically monitored in a production process. Product quality will typically be defined by two quantities: deviations from stated ...

In biopharmaceutical manufacturing, consistency is vital but hard to achieve. Turning raw materials into safe, high-quality medicines requires stable processes. However, the living cellular expression ...