The CFTR Protein Distribution Core offers high-quality, full-length recombinant cystic fibrosis transmembrane conductance regulator (CFTR) proteins expressed in and purified from mammalian cells. Wild ...

In this article, we take a look at five biotech companies developing potentially transformative medicines to treat cystic ...

The CFTR protein reaches the cell membrane but the ... chloride from week 16 to week 40 VX-770: 2.2 mEq/L ± 12.2 CF = cystic fibrosis; CFQ-R = Cystic Fibrosis Questionnaire-Revised; FEV 1 ...

CF often arises from mutations that make the cystic fibrosis transmembrane conductance regulator (CFTR) protein misfolding and malfunction, causing thick mucus to aggregate in the lungs while also ...

Technically demanding protocols and reagents for cloning and propagating adenoviral and other recombinant viral systems, advances in gene suppression technology with sh- or siRNA, and capabilities for ...

Cystic fibrosis is caused by faults in a gene called CFTR, which gives the body “instructions” to produce a protein that ...

Maternal health outcomes in women with cystic fibrosis are improved with use of certain types CFTR modulator therapy.

With new approvals on the horizon and the closely watched Casgevy launch picking up steam in sickle cell disease and beta ...

An estimated 105,000 people have been diagnosed with CF across 94 countries, according to the Cystic Fibrosis Foundation. The absence or dysfunction of the CFTR protein results in a defect in ...

An international study has identified two types of these so-called dysbioses in cystic fibrosis. They display ... Landmark Study Involving Babies in Ireland Supports Use of Cystic Fibrosis Drug in ...