How Does Cialis Work? Like other PDE5 inhibitors, Cialis blocks an enzyme known as phosphodiesterase type 5 (PDE5) in the spongy part of the privates.

Cialis and Viagra both work in very similar ways and have similar effects on your arousal. Cialis and Viagra, as well as their generic equivalents, belong to a class of drugs referred to as PDE5 ...

But does it really work? Here's what professionals have to say. ... (Cialis) “are better options for helping [males] get good erections than supplements such as Virectin,” Shteynshlyuger says.