Researchers found that caffeine blocks alcohol’s ability to increase dopamine in brain reward areas, potentially reducing ...

A team of neurologists, bioengineers and radiologists has found that two neurons in the human brain that code for dopamine ...

People with chronic cocaine use can experience cognitive impairments and motor dysfunction that can be mitigated with antioxidant or anti-inflammatory agents; this supports the authors’ claim that ...

New evidence suggests that prenatal exposure to tetrahydrocannabinol (THC) could increase the risk of opioid addiction later ...

There are three dopaminergic pathways, namely the striatonigral pathway (substantia nigra to caudate and putamen), the mesolimbic pathway (ventral tegmental area of midbrain to limbic areas of ...

Unlike dopaminergic therapies, which primarily act by replenishing, enhancing, or mimicking dopamine, solengepras is designed to selectively address the indirect pathway by modulating the GPR6 ...

in particular those associated with the nigrostriatal dopaminergic pathway. There is now robust experimental evidence for a neuroprotective effect of nicotine upon dopaminergic neurons.

Precision drugs and gene therapy treatments to activate pro-survival pathways in selected neuronal populations We investigate molecular mechanisms promoting functional maintenance of dopaminergic ...