Two decades of cloning experiments in mice have produced a striking pattern: animals created through somatic cell nuclear ...

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...

Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refining data, conducting massive trials, before unveiling results that altered the ...

According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning ...

Embryonic stem cells (ESCs) exhibit unique chromatin features, including a permissive transcriptional program and an open, decondensed chromatin state. Induced pluripotent stem cells (iPSCs), which ...

ER-300 improves key biomarkers of liver health in an animal model of MASH These data, along with additional ER-100 preclinical data from a nonhuman primate model of NAION demonstrating clear ...

Researchers developed FLAV-27, an epigenetic drug that inhibits G9a to restore gene expression in Alzheimer’s models. The ...

Cancer immunotherapy has transformed the treatment landscape for multiple malignancies; however, its clinical efficacy remains limited in many tumors due to ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as ...