In some cases, agonists selectively bound to the higher molecular weight form, consistent with the notion that the functional unit of GPCR is a dimer/oligomer. The isolation of cDNA clones ...

At the interface between these circulating factors and insulin/glucagon secretion are GPCRs, which in islets mediate the effects of many of the circulating factors, such as glucagon-like peptide-1 ...

Septerna may be yet to disclose “any meaningful clinical data,” but the biotech clearly thinks there will be investor appetite for its G protein-coupled receptors (GPCRs). The South San ...

Structure Therapeutics Inc. (NASDAQ:GPCR) was able to report positive results from its phase 2a study using its GLP-1R agonist GSBR-1290 for the treatment of patients with obesity in June 2024.

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