After years of near eradication, kernicterus, a neurologically devastating condition caused by neurotoxic levels of bilirubin in the first week of life, has reemerged as a significant problem in ...
Conjugation of bilirubin and delivery to the intestine doesn't necessarily lead to excretion of the substance. Neonatal intestines contain beta-glucuronidase, an enzyme capable of reducing ...
Clinicians need to monitor it carefully and sometimes treat it, since it can lead to conditions like acute bilirubin ...
According to the NHS, while neonatal jaundice is common there are rare cases where the bilirubin levels are so high there’s a risk the baby could develop kernicterus (permanent brain damage).