Light-sheet microscopy uses a thin plane of light to illuminate a sample orthogonally to the detection objective such that the axial resolution of the microscope is determined wholly or partly by the ...

Since 2004, when the first paper on light-sheet microscopy (aka selective plane illumination microscopy, or SPIM) appeared (Science, 305:1007-09), users of the technique have coalesced into a growing ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Tools that allow neuroscientists to record and quantify functional activity within the living brain are in great demand. Traditionally, researchers have used techniques such as functional magnetic ...

Using lattice light-sheet microscopy, it is possible to make continuous fluorescence movies of developing organisms with no phototoxic effect. Lattice patterns are typically adjustable and can ...

Greenland is the second largest permanently ice-covered surface on the Earth; only Antarctica is larger. The Greenland ice sheet is drastically impacted by the effects of climate change. If the ice ...