Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

More than 10,000 Americans are waiting for a liver transplant. Many more never make the list, because they are too sick to ...

Your liver performs over 500 essential functions every single day, yet most people remain completely unaware when this vital organ begins failing until damage reaches catastrophic levels that may be ...

Cirrhosis is the result of long-term liver injury where healthy tissue is replaced with scar tissue (fibrosis). Common causes of cirrhosis include alcohol use disorder (AUD), nonalcoholic fatty liver ...

Over time, this damages liver cells, triggers inflammation and contributes to fibrosis, which is the build-up of scar tissue. If scarring becomes extensive, it can progress to cirrhosis, a stage where ...

Dr. Chander Negi prepares samples using the PhysioMimix LC12 liver-on-a-chip system as Dr. Ivan Rusyn looks on in their Texas A&M research laboratory. Creating a drug that might help treat or cure a ...

Hepatitis B is one of the most widespread viral infections in the world, with hundreds of millions of people living with it today. Caused by the hepatitis B virus (HBV), this condition primarily ...