Freidlin and Korn 9 critically review some of the alternative methods. Their conclusion is that these methods can be useful as secondary analyses, but they are not ready to be used in primary analysis ...

In two-stage adaptive treatment strategies, patients receive an induction treatment followed by a maintenance therapy, given that the patient responded to the induction treatment they received. To ...

For large-sample clinical trials with independent individuals randomly allocated to two treatment groups, in which survival times follow a log linear multiplicative intensity model with treatment ...

Novel Use of Patient-Specific Covariates From Oncology Studies in the Era of Biomedical Data Science: A Review of Latest Methodologies A statistical test for the presence of treatment effects on ...