U.S. District Judge Dale Ho said Adams failed to demonstrate that federal prosecutors leaked grand jury secrets to the media, ...

Midcoast Youth Center & Skatepark will host Strengthening Families Program (SFP) facilitator training Friday through Sunday, ...

Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is ...

Complementary to other molecular techniques: OGM provides a complementary approach by revealing large structural variations that may be missed by methods like next-generation sequencing (NGS). A ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...

We have identified the IRE1/XBP1 branch of the Unfolded Protein Response (UPR) or endoplasmic reticulum (EnR) stress response as a previously unexplored therapeutic vulnerability in MYC-driven breast ...

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Multiple myeloma, a hematologic cancer, is marked by genetic abnormalities, including MYC gene rearrangements. The study showed that OGM detected MYC-positive cases in 40% of instances compared to ...