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Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.
Christopher J. Fallaize, Peter J. Green, Kanti V. Mardia, Stuart Barber, Bayesian protein sequence and structure alignment, Journal of the Royal Statistical Society ...
Edgar calls his new algorithm MUSCLE (multiple sequence comparison by log expectation). MUSCLE uses a log expectation score to control progressive alignment of the input amino acid sequences. This ...
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