The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ...

Mrep accumulates in damaged muscle tissue and promotes muscle regeneration by acting on muscle satellite cells through activin A. While Mrep performs beneficial functions in normal muscle repair, in ...

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells. Similar to the instant kung fu ...

MHH researchers have deciphered the signalling pathway that controls the movement of mitochondria within cells during heart development. The original paper “RHOT Proteins Link Mitochondrial Motility ...