How oligodendrocytes use fatty acid metabolism as an energy reserve to maintain axonal function and myelin stability when glucose is scarce, offering insights into neurodegenerative disease ...
Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a ...
Researchers found a molecule, sulfuretin, can promote myelin repair, slowing disease progression in MS and some cancers.
The investigators focused on brain cells called human oligodendrocyte progenitor cells (OPCs), which can transform into the cells that generate myelin: oligodendrocytes. However, in MS, inflammation ...
Donor-derived MBP+ oligodendrocytes and myelin (red) are evident in the corpus callosum, while donor-derived GFAP+ astrocytes (green) predominate on the striatal side. Scale bar, 1 mm (a-c), 100 ...
In some cases, the body also attacks another protein known as myelin oligodendrocyte glycoprotein. This activates other parts of the immune system and causes inflammation and damage to myelin.
On this week’s program, Dr. Joe Sirven examines advancements in multiple sclerosis research and common sleep disorders in ...
This study uncovers the ketogenic diet's effects on the microbiome, revealing its potential to mitigate autoimmune diseases through metabolic pathways.
Research published in the journal Glia has identified crucial links between dietary choices and the progression of multiple ...
Myrtelle’s FIH trial utilizes the Company’s proprietary rAAV vector to directly target oligodendrocytes, the brain cells affected in CD which are responsible for producing myelin – the ...
Senior linebacker Jordan Zaragoza has become a key player for the United Longhorns, overcoming a serious health scare to lead the defense.