The overwhelming majority of genes in the human genome encode RNA molecules that are not translated into proteins. These RNA molecules are named non-coding RNAs (ncRNAs). ncRNAs play a crucial ...

The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and ...

We mapped the human genome decades ago, but most of it is still a black box. Now, UNSW scientists have developed a tool to ...

This development not only provides a valuable tool for studying non-coding RNAs, but also opens new avenues to create new biocatalysts capable of targeting disease-associated RNA species.

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that ...

Their findings, recently published in Nucleic Acids Research, spotlight TERRA—a long non-coding RNA transcribed from the ends of chromosomes—as a potential biomarker for age-related and ...

A liquid biopsy diagnostic that detects noncoding RNA in addition to protein-coding RNA improves early stage cancer diagnosis.

One of the things we learned in this study is that the deletion of a specific long non-coding RNA changes the expression of a particular gene called CHD2.

Kim’s lab developed an RNA liquid biopsy platform that detects both protein-coding RNA and RNA dark matter in the blood, and showed that this new approach significantly improves the performance of ...

Transfer RNA fragments (tRFs), small non-coding RNA pieces generated by enzymatic cleavage, are emerging as potential indicators of neurological disorders.