On the right side, select the Open checkboxes for the file types that you want to open in the Protected View. Now, select the Open selected file types in Protected View radio button at the bottom.

Learn how to use a Microsoft 365 setting to choose whether to open files in the online or desktop app, giving you full control for each file.

Learn how to open an XML File in Excel, Word, Chrome, and Edge on a Windows computer using the methods mentioned in this post.