Katie Szyman, who led Edwards Lifesciences Corp.’s Critical Care unit that was recently sold for $4.2 billion, says ...

More than 50 kittens and cats were discovered in an Irvine home where a woman was allegedly breeding and selling them for up to $1,000, the Irvine Police Department said Wednesday. Some of the ...

Surveillance footage at the Irvine home of a slain disabled man showed that it was his ex-caregiver who crashed a minivan into the garage before forcing his way into the house and fatally stabbing ...

IRVINE, Calif. (KABC) -- Residents at Park West Apartments in Irvine describe the community as calm and mellow. Guadalupe Sosa has lived here for two years and has never had any issues. "The ...

IRVINE, CA — A package theft suspect was arrested this week by Irvine police officers with the help of community members, ...

Click to turn the feature on or off. Learn more about this technology here. In Irvine, the mayor is an at-large member of the city council, which means they represent the city as a whole ...

IRVINE, Calif. - Two people are dead outside a home in Irvine Thursday afternoon. It happened around 3:30 p.m. The Irvine Police Department said officers were called out to the area of Green Tree ...

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A 157,500-square-foot office building in Orange County has sold to a technology manufacturer to use as its global ...

Irvine officials were set to approve changes to their lobbying law in a final vote Tuesday night. Instead, they ended up making additional changes and reintroduced the new rules.

Video game giant Activision Blizzard will start laying off employees at its Irvine and Santa Monica locations next month as parent company Microsoft Corp. looks to cut costs in its gaming division.

IRVINE — Irvine’s boys water polo team united Wednesday to beat a former league rival and a former coach. Seniors Sean Dory and Xavier Mao each scored three goals as the Vaqueros rallied to ...