New take on immunotherapy reinvigorates T cells by blocking uptake of energy-sapping cancer byproducts
As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T ...
technologynetworks2d
Exposure to “Danger Signals” Can Prime the Innate Immune System Into a Long-Term Inflammatory State
Brief exposure to "danger signals" can prime the innate immune system into a long-term hyperreactive and inflammatory state.
Too Old to Operate4d
Altered p53 and Cell Cycle Regulation in SCZ Neural Progenitors
The following is a summary of “Patient iPSC-derived neural progenitor cells display aberrant cell cycle control, p53, and DNA ...
BioSpace5d
Sana Biotechnology Will Lay Off Employees as It Shifts Pipeline
About a year after cutting staff by 29%, Sana Biotechnology will trim its workforce as it increases investment in its type 1 ...
News Medical on MSN2d
New approach reinvigorates exhausted T cells to improve tumor control
As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic ...
Obesity Breakthrough: Promising New Treatment Found To Curb Fat Formation
Electro-acupuncture may help manage obesity by reducing osteoprotegerin, a protein tied to fat cell growth. This TCM approach ...
GEN2d
Cancer-Fighting Zeal Regained by Tired T Cells Deprived of Lactic Acid
Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...
The Scientist10d
Meet Cyclone: A Monitoring Tool That Watches for Waves of Immune Response
We wanted to create a monitoring tool that helps clinicians understand what is going on in the patient at a precise level, ...