While antisense oligonucleotide and aptamer drugs have been on the market ... employed to fight against the COVID-19 pandemic that RNA-based therapeutics attracted the attention of the general ...

A research team has developed an RNA-based sensor platform that can regulate ... for sensors that require high selectivity. When an aptamer binds to its target, it triggers a structural change ...

The PP7 coat protein–RNA interaction was first adopted by Kathleen Collins' group at the University of California, Berkley to design an aptamer for affinity purification of ribonucleoproteins ...

A small molecule-type ligand blocked cleavage by binding with RNA aptamer sequences, thereby retaining intact mRNA and inducing transgenic expression. The Y-shaped structure of aptamers could ...

The AptaFluor SAH Methyltransferase Assay uses a highly sensitive RNA aptamer that is capable of directly detecting SAH. The sensitivity of the aptamer (measures SAH at concentrations below 10 nM ...

Aptamers are short strands of nucleic acids (DNA or RNA) that bind specifically and ... for sensors that require high selectivity. When an aptamer binds to its target, it triggers a structural ...

In this Q&A, learn more about how Heonjoon Lee, fifth year biomedical engineering PhD student, found his niche in ...