An international, randomized, double-blind, placebo-controlled Phase III study—the largest of its kind for mpox—found that tecovirimat did not improve clinical outcomes for adults with clade II mpox ...
Randomized, placebo-controlled Phase 2a study of SPL026 met its primary endpoint demonstrating a clinically significant reduction in depressive ...
Utility of the 70-Gene MammaPrint Assay for Prediction of Benefit From Extended Letrozole Therapy in the NRG Oncology/NSABP B-42 Trial Patients with advanced lung cancer reporting at least moderate ...
Despite a trend toward more patient-centered research, quality-of-life end points remain substantially underreported in phase ...
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New global guidelines improve reporting of pediatric randomized controlled trials
Researchers at The Hospital for Sick Children (SickKids), working with international collaborators and youth and family ...
Six hundred trials from high-impact medical journals were classified depending on whether they allowed for the inclusion of patients with localized and/or metastatic disease. Five hundred trials were ...
AMSTERDAM — At least one third of patients with major depressive disorder (MDD) would not qualify for inclusion in many randomized controlled trials (RCTs) that help guide the use of antidepressants, ...
‘A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial’ by David Erritzoe et al. was published in Nature Medicine at 16:00 UK time on ...
Conflict of interest reporting is flawed and inconsistent across clinical trials assessing the effectiveness of corticosteroid injections in knee osteoarthritis, according to data published in ...
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