A Korean research team has successfully proposed a new cause for the onset of dementia, a condition that has been difficult to treat and prevent due to its previously unknown origins. This discovery ...

Astrocytes, the predominant glial population in the human central nervous system, play crucial roles in neuroprotection, immunity, and homeostasis. However, when exposed to certain neuroinflammatory ...

In neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS, excessive H2O2 from reactive astrocytes triggers a vicious cycle of oxidative stress, protein aggregation, and neuronal loss.

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

How do astrocytes react to Alzheimer’s disease pathology? It’s complicated, according to the largest single-nuclei RNA-Seq study of these cells published thus far. Scientists led by Sudeshna Das at ...