CLEC-1 is a death receptor and binds to dead cells induced by secondary necrosis. We have discovered that CLEC-1 represents a novel type of myeloid checkpoint within the C-Type Lectin family ...
Programmed cell death 1 (PD-1) is an important target for immune checkpoint inhibitor therapies that block its signaling and boost T-cell activity. PD-1 inhibitors have been approved for treating ...
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