Deciphering Cellular Networks from Gene Expression Data, Phosflow Assays & Pathogens Signaling networks within cells play a role in virtually every process from differentiation and proliferation to ...
Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...
Edited by: Karen Young Kreeger N. Funayama, F. Fagotto, P. McCrea, B.M. Gumbiner, "Embryonic axis induction by the armadillo repeat domain of b-catenin: Evidence for intracellular signaling," Journal ...
A number of cellular processes are initiated by the binding of ligands, such as hormones, neurotransmitters or cytokines to specific receptors in the cell membrane. “Signal transduction has to be ...
Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2
In recent years, immune checkpoint therapy headed by programmed death receptor 1 (PD-1) and programmed death receptor-ligand 1 (PD-L1) has been proven to be safe and effective. However, clinical ...
Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the ...
A team of researchers from Florida International University (FIU) examined a brain protein previously associated with brain inflammation in Alzheimer's patients, in an effort to gain a deeper ...
"Bloody Hot" Field: Because the signaling protein Stat5 has been found to be active in numerous pathways, many researchers are engaged in studying its various roles, says James Ihle. M. Azam, H.
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