Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Resistance to therapy and tumor heterogeneity remain the fundamental drivers of treatment failure in oncology. While single-agent therapies have provided ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well ...

Artelo Biosciences, Inc. (Nasdaq: ARTL), a clinical-stage pharmaceutical company focused on modulating lipid-signaling pathways to develop treatments for people living with cancer, pain, dermatologic, ...

This might be a long shot, but I was diagnosed with triple negative breast cancer, had a lumpectomy with clear margins and had a recurrence six months later. I am struggling with the treatment regimen ...

Virus-associated cancers are a significant and persistent global health challenge, providing unique insight into the relationship between chronic infection ...

This biological process, where mature, specialized cells lose their distinct characteristics and revert to a more primitive, aggressive state, is a universally recognized sign of poor prognosis across ...

Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

Researchers from two labs in the Human Biology division at Fred Hutch Cancer Center recently published two studies aimed at better understanding how a notorious gene fusion — ZFTA-RELA — drives rare ...