Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

Wiring up the brain's trillions of circuit connections is an enormous job performed by a huge crew of molecules. Among the less understood members are circular RNAs, transcripts from DNA that assume a ...

Establishment of neural circuits is a tightly regulated process coordinated by a series of cellular and molecular mechanisms. Within the neural circuitry electrical and chemical information is ...

Mitochondria, the tiny power plants inside all plant and animal cells, play a critical role in the health and well-being of synapses, neuroscientists at MIT's Picower Center for Learning and ...

New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications ...

JUPITER, FL--Making memories involves more than seeing friends or taking photos. The brain constantly adapts to new information and stores memories by building connections among neurons, called ...

Case Western Reserve University's Institute for Functional Restoration (IFR) and Synapse Biomedical Inc. have entered a partnership to commercialize fully implantable systems that restore muscle ...

Synapses are the power junctions that allow living creatures to function. Popularly associated with learning and memory, they play a more fundamental role in our existence by regulating everything ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 21 (Oct. 10, 2000), pp. 11581-11586 (6 pages) Studies of sensitization and classical conditioning of the ...