Intravital brain imaging is a valuable tool for studying neurons, glial cells, and their surroundings in living animals. It allows the investigation of neurological illnesses, therapeutic efficacy, ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Researchers used a two-photon phosphorescent probe to monitor capillary flux and oxygen in sets of capillaries, obtaining a robust oxygen and flux estimate within each capillary, sufficient to observe ...

Intravital brain imaging is a powerful method for observing neurons, glial cells, and their surrounding environments in living animals. It facilitates the study of neurological diseases, drug efficacy ...

Multiphoton microscopy is used in biomedical research to study cells and tissues. Today, so-called two-photon microscopy is used to study processes within cells, but the technique has limitations in ...

A newly described technology improves the clarity and speed of using two-photon microscopy to image synapses in the live brain. The brain's ability to learn comes from "plasticity," in which neurons ...

High-resolution images without expensive microscopy equipment. The aim of the EU-funded project “4 for 2” was to develop a new category of smart molecules for labelling cells, enabling more efficient ...

In-vivo imaging of the neuronal activity in mouse primary visual cortex. Left, high-resolution neuronal map; middle, high-speed neuronal activity recording captured by the two-photon microscope with ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...