It's only during the last few decades that neuroglia, a diverse group of cells found in the brain that perform a variety of ...
Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...
Researchers from Tohoku University discovered that part of the memory selection process depends on the function of astrocytes ...
Researchers at the Max Planck Institute (MPI) for Multidisciplinary Sciences have now shown that, in addition to neurons, special glial cells in the brain also produce amyloid beta. This finding ...
Deletion of the ‘glial cells missing-2’ gene in mice disrupts development of the parathyroid glands but does not eliminate production of parathyroid hormone (PTH), which is required for ...
Although systemic treatments like chemotherapy are effective at eliminating cancer cells throughout the body, they are unable to penetrate the brain, leaving it vulnerable to metastasis. Fifty percent ...
How does the brain store—and access—our memories? While our understanding of the brain has (thankfully) developed greatly from the days of removing cerebral tissue to see what would happen, a precise ...
Scientists have successfully reprogrammed astroglia, a type of brain support cell, into neurons that mimic specific ...
The scientists deployed a barrage of genetic tinkering in fly and cell culture models. First, they took advantage of the massive compound eye of the fly, in which bundles of retinal photoreceptor ...
The primary focus in the laboratory is on ion channels that regulate specification, migration and differentiation of these glial cells. The oligodendrocyte generates CNS myelin, which is essential for ...
The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms.
One of their major efforts was the study of laminin receptors on Schwann cells, the myelinating peripheral glia. By generating and comparing animal models of demyelinating neuropathies to patient's ...