Observational analyses can complement randomized clinical trial findings for the study of HPV vaccine effectiveness

Led by researchers at NDORMS as part of the Data Analysis and Real World Interrogation Network (DARWIN EU) initiative, a new ...
ascopubs.org

Final Overall Survival Analysis of S1500: A Randomized, Phase II Study Comparing Sunitinib With Cabozantinib, Crizotinib, and Savolitinib in Advanced Papillary Renal Cell Carcinoma

Correlative Science in the Cooperative Group System: Re-Engineering for Success Clinical trials frequently include multiple end points that mature at different times. The initial report, typically ...

Multi-strain probiotic therapy shows promise in preventing bacterial vaginosis recurrence

A global team of experts has identified a promising new approach to prevent recurrence of bacterial vaginosis (BV), a ...

New Research Reveals a Simple Supplement May Slow Biological Aging

Researchers led by Mass General Brigham report that older adults who took a daily multivitamin for two years showed signs of ...
ascopubs.org

Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial

First Results of NURE-Combo: A Phase II Study of Neoadjuvant Nivolumab and Nab-Paclitaxel, Followed by Postsurgical Adjuvant Nivolumab, for Muscle-Invasive Bladder Cancer Preventive use of naldemedine ...
The New England Journal of Medicine

A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt surgery, ...