Ischemic stroke in younger adults is far less common than that among older adults, yet the underlying pathogeneses and risk factors are more diverse. Approximately 10% to 15% of all strokes occur in ...

Background—MicroRNAs (miRs) are small noncoding RNAs that posttranscriptionally control gene expression. Small-animal studies suggest that miRs might offer novel therapeutic targets in cardiovascular ...

Smooth muscle cell migration occurs during vascular development, in response to vascular injury, and during atherogenesis. Many proximal signals and signal transduction pathways activated during ...

In the present study, we recruited 231 women with chronic hypertension, including those who received amlodipine or other antihypertensives during early pregnancy, and investigated frequencies of ...

Background— The ability to derive human induced pluripotent stem (hiPS) cell lines by reprogramming of adult fibroblasts with a set of transcription factors offers unique opportunities for basic and ...

Cardiovascular disease (CVD) remains a major health burden despite significant therapeutic advances accomplished over the last decades. It is widely and increasingly recognized that systemic ...

Aim: The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family screening, medical ...

These guidelines contain recommendations for pediatric basic and advanced life support, excluding the newborn period, and are based on the best available resuscitation science. The Chain of Survival ...

Atherosclerotic renovascular disease is the most frequent cause of renovascular hypertension and its prevalence increases with age and in specific subset of patients, such as those with end-stage ...

Coronary computed tomography angiography (CCTA) has long been considered a gatekeeper for invasive coronary angiography because of its high sensitivity and negative predictive value. However, there ...

Measurement of blood pressure (BP) in the upright posture is recommended by all hypertension guidelines to detect orthostatic hypotension especially in elderly patients. 1 However, a number of studies ...

We analyzed data from 113 918 newly diagnosed patients with dyslipidemia (2009–2012) without prior CVD, sourced from the Korea National Health Insurance Service. Ambient particulate matter (PM) 2.5 ...