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CIRM Approves New and Updated Funding Programs, Awards $26.5 Million for Clinical Research and Development

South San Francisco, CA, March 27, 2025 — The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, approved new and ...
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Clinical Trial Stage Projects

The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs. With our Clinical Stage Programs, we intend to speed up ...
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Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers.

Marty G Yang, Hannah J Richter, Simai Wang, Colin P McNally, Nicole Harris, Simaron Dhillon, Michela Maresca, Elzo de Wit, Holger Willenbring, Jacquelyn Maher, Hani Goodarzi, Vijay Ramani We present a ...
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Protocol to study ductal progenitor-like cells from the adult human pancreas using 3D suspension and methylcellulose-based culture systems.

The pancreas is comprised of two compartments, the exocrine and endocrine. The exocrine acinar cells produces and secreted digestive enzymes that are carried by ductal cells to the duodenum, whereas ...
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Stem Cell-Based Cartilage Tissue Regeneration

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Phase I/II Clinical Trial for CMT4J

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Scribe Therapeutics

Preclinical Stage Projects Maria Mirotsou A First-in-Class CIRSPR-CasX Gene Editing Therapy for Lowering Lp(a) to Prevent Cardiovascular Events $12,714,480 Preclinical Stage Projects Brett Staahl A ...
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4D Molecular Therapeutics, Inc.

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Clinical Development of ETX101, a Gene Regulation Therapy for SCN1A+ Dravet Syndrome

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Astroglia’s role in synchronized spontaneous neuronal activity: from physiology to pathology.

The brain depends on a careful balance between signals that excite neurons and those that calm them down. When this balance is lost and neurons become overly active, it can lead to serious ...
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Demographics, Prevalence, and Characteristics of Limbal Stem Cell Deficiency in Southern California.

Limbal stem cell deficiency (LSCD) is a potentially blinding disease characterized by the loss of the stem cell population. The purpose of this publication is to report the prevalence, incidence and ...
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Androgenetic alopecia.

Yingzi Liu, Antonella Tosti, Etienne C E Wang, Stefanie Heilmann-Heimbach, Crystal Aguh, Francisco Jimenez, Sung-Jan Lin, Ohsang Kwon, Maksim V Plikus Androgenetic alopecia (AGA) is a condition of ...