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Specific input parameters for NH130, such as molecular weight, logarithm of the partition coefficient (LogP), acid dissociation constant (pKa), and solubility, were essential to predict NH130 ADME.
1 Department of Neurobiology and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, United States 2 Department of Neurobiology, Physiology, and Behavior, Center for ...
To estimate the in silico pharmacokinetic parameters of each one of the compounds, some web based in silico pharmacokinetic tools were used by submitting the chemical structure in the form of ...
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