The 49ers might have to start their fifth different safety of the season this Sunday. That's because rookie safety Malike Mustapha is questionable with a calf injury. He missed Wednesday's ...

The 49ers and Buccaneers have been dealt with major injury blows. With Christian McCaffery slated to come back from the IR and Mike Evans and Chris Godwin out, the Buccaneers are in worse shape than ...

SANTA CLARA -- When the 49ers respect a quarterback, you can tell. They'll always praise their upcoming opponent. But when they face someone average or worse, they say things like they have to ...

The NFL issued an $11,255 fine to San Francisco 49ers defensive end Nick Bosa for sporting a MAGA hat on the field following Week 8's 30-24 win over the Dallas Cowboys. During a postgame interview ...

The San Francisco 49ers will travel to Tampa Bay in Week 10 to face the Buccaneers at Raymond James Stadium. The matchup is set to kick off at 10 a.m. PT on Sunday, November 10. Here are all the ...

SANTA CLARA, Calif. -- After observing Christian McCaffrey participating in the San Francisco 49ers' most strenuous practice of the week, coach Kyle Shanahan said he has seen enough to believe ...

The Tampa Bay Buccaneers (4-5) will be attempting to end a three-game losing run against the San Francisco 49ers (4-4). The 49ers are the favorites, expected to win by at least a field goal but ...

Heading into the second half of a season where seemingly nothing has gone right, the 49ers are doubling down. At 4-4, but with a Super Bowl window that the team believes is still wide open ...

San Francisco 49ers head coach Kyle Shanahan told KNBR on Thursday that he expects all-everything running back Christian McCaffrey — who has been on injured reserve since Sept. 14 with bilate ...

Out since the start of the regular season with Achilles tendinitis, reigning Offensive Player of the Year Christian McCaffrey finally returned to practice with the San Francisco 49ers this week.