After an illustrious career, including 12 years as director of the NIH and leading the HGP consortium, Francis Collins announces his sudden resignation.

Francis Collins, a renowned geneticist and former longtime director of the National Institutes of Health, has retired, ...

Hello, and welcome to Post Live. I’m Akilah Johnson, a national health reporter focused on health disparities here at The Washington Post. And today we have two segments on rare diseases. Later, we'll ...

The trial specifically focuses on adults with CF who genetically cannot benefit from cystic fibrosis transmembrane conductance regulator ... by inserting a functional copy of the CFTR gene in the DNA ...

Any disease can cause problems in other parts of your body. Your doctor will call these complications. Myelofibrosis is no exception. There’s no guarantee you’ll have other problems.

Findings from a new study highlight key differences in the gut microbiome of infants with cystic fibrosis (CF ... The team used DNA sequencing techniques to analyze the bacterial composition ...

Researchers have been trying for decades to stop the cells that damage the lung in people with pulmonary fibrosis. Now a team of Columbia and UCSD researchers may have found a clever solution that ...

A hallmark of cystic fibrosis (CF) chronic respiratory disease is an extensive ... chronic bacterial infection in the airways. 3. release of DNA: CF neutrophils are continuously stimulated in ...

RHH proteins share a low sequence identity but have similar structures, despite multiple insertions and deletions between the α-helices of this small domain. DNA binding does not alter the ...

Prognosis of patients with cystic fibrosis (CF) varies extensively despite recent advances ... Although clinical translation of DNA or RNA therapy has been proven feasible, the efficient targeting and ...

Remarkably, our experiments show that the DNA sequence directly encodes the structure of supercoiled DNA by pinning plectonemes at specific sequences. We develop a physical model that predicts that ...