Multiple myeloma (MM) is an incurable blood cancer, leading to weakened immunity, bone damage, and other serious health ...

This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

Dendritic cells—the immune system's best antigen-presenting cells—carry proteins on their surfaces that help them recognize ...

Dendritic cells (DCs) are critical in the maintenance of self-tolerance and altered functions of DCs have been implicated in the pathogenesis of a number of autoimmune diseases, such as rheumatoid ...

Plasmacytoid dendritic cells (pDCs) are a unique subset of immune cells originating from the bone marrow, playing a crucial ...

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of ...

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

Research shows nanobodies surpass traditional antibodies in cancer vaccine delivery, offering faster production and equal targeting precision while reducing complexity and costs.

The heart tissue showed upregulation of molecular pathways that help recruit and retain immune cells involved in inflammation. Patients with active disease also had greater abundance of clusters of ...

“DOC1021 is a first-of-its kind double-loaded dendritic cell vaccine that represents an entirely new strategy for engaging a complete immune response against a patient’s cancer,” said Mike ...

The article is titled "Pyruvate–GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells." When they tested how different metabolites affected cDC1 cells ...

Scientists develop technique using palladium-tagged particles to track nanoplastic interactions with immune cells, showing ...