Rest tremor in Parkinson’s disease is linked to dopamine activity in the caudate nucleus, challenging conventional beliefs about dopamine loss and motor symptoms.

Unlike dopaminergic therapies, which primarily act by replenishing, enhancing, or mimicking dopamine, solengepras is designed to selectively address the indirect pathway by modulating the GPR6 ...

People with chronic cocaine use can experience cognitive impairments and motor dysfunction that can be mitigated with antioxidant or anti-inflammatory agents; this supports the authors’ claim that ...

New evidence suggests that prenatal exposure to tetrahydrocannabinol (THC) could increase the risk of opioid addiction later ...

Researchers found that caffeine blocks alcohol’s ability to increase dopamine in brain reward areas, potentially reducing ...

Contrary to the belief that the path to sustainable development is increasingly out of reach, the results show that humankind has a variety of pathways to depart from its current unsustainable ...

The alternative complement pathway plays a key role in the pathogenesis of IgA nephropathy. Iptacopan specifically binds to factor B and inhibits the alternative pathway. In this phase 3 ...

Taken together, the findings suggest that environmental adaptations influence behavioral traits and sensitivity to nicotine by acting on dopaminergic activity in response to nicotine exposure, ...

Agencies have a new way to connect with qualified early-career workers and move them from the Pathways Program into full-time federal jobs. Two new “talent programs” on USAJobs, which the Office of ...

Some words may be mispronounced. CEDAR RAPIDS — Pathways in medical sciences, aviation and engineering, agriculture, education and technology are just a few of the careers students in the Cedar ...