Image Caption: The human and mouse expression profile of FGF8. (A) Relative abundance of FGF8 in adult human tissues from the Genotype-Tissue Expression (GTEx V8) Project Consortium (TPM, transcripts ...

Nager syndrome (NS) is an extremely rare disease that causes developmental problems and anomalies in facial bone structures and limbs. While the causative gene is known, its underlying mechanisms ...

In this manuscript, Karl et al. explore mechanisms underlying the activation of the receptor tyrosine kinase FGFR1 and stimulation of intracellular signaling pathways in response to FGF4, FGF8, or ...

I'm trying to follow the Differential Expression Analysis for CCC & Downstream Signalling Networks["https://liana-py.readthedocs.io/en/latest/notebooks/targeted.html ...

In the interests of transparency, eLife publishes the most substantive revision requests and the accompanying author responses. [Editors' note: this paper was reviewed by Review Commons.] Reviewer #1 ...

An international team of scientists from Michigan State University recently sequenced the genome of the bowfin fish (Amia calva). The study is shedding more light on a species that has long been ...

The tuberal hypothalamic ventral premamillary nucleus (VPM) described in mammals links olfactory and metabolic cues with mating behavior and is involved in the onset of puberty. We offer here ...

Cleft lip and cleft palate are birth defects that occur when a baby’s lip or mouth do not form properly during pregnancy. About 1 in every 1,600 babies is born with these defects in the United States, ...

Hepatoblastoma (HB) is the most common pediatric liver tumor with a general good prognosis, but if associated with multifocal growth, vessel invasion or metastasis, outcome is still poor. The ...

How are the body’s segments formed? The body of a vertebrate organism consists of segmented axes, which is most distinct in the skeleton. The process of somitogenesis is key to the development of ...

The cochlea is essential for sound detection. It consists of highly differentiated hair cells and nonsensory supporting cells radially patterned into lateral and medial compartments. However, ...