Introduction to HEK 293 Cells HEK 293 cells, also known as Human Embryonic Kidney 293 cells, have become a crucial tool in ...

Septerna’s platform technology enables scientists to isolate a GPCR and study it outside of a cell, but in a way that replicates what happens to that receptor inside a cell. With this greater ...

Tokyo, Japan and London and Cardiff, UK, 5 November 2024 - Nxera Pharma ("Nxera”; TSE 4565) - formerly known as Sosei Group ...

Septerna may be yet to disclose “any meaningful clinical data,” but the biotech clearly thinks there will be investor appetite for its G protein-coupled receptors (GPCRs). The South San ...

Septerna's shares rose about 31% in their market debut on Friday, giving the Goldman Sachs-backed biotech firm a valuation of ...

Using a platform for isolating functional native GPCR proteins outside of cells, Septerna has created a small molecule, SEP-786, that could offer hypoparathyroidism patients an oral alternative to ...

GPCRs are a group of proteins in the cell membrane that receive signals and convert them into physiological effects. Structure Therapeutics (NASDAQ:GPCR) is also developing innovative treatments ...

Specifically, in the presence of metabolite pyruvate, these cells extend dendrites to sample ... known as G protein-coupled receptors (GPCRs), can detect these metabolites and trigger important ...

A group of proteins in our body, known as G protein-coupled receptors (GPCRs), can detect these metabolites ... formation in human intestinal dendritic cells." When they tested how different ...

With their unique structure, nanodiscs improve drug delivery and vaccine development, stabilizing membrane proteins for ...

California-based Septerna is developing therapies targeting G-protein-coupled receptors (GPCR), a class of proteins that serve as a main conduit for chemicals to get past a cell's membrane and be ...

ORs are members of the superfamily of membrane-bound proteins known as G-protein-coupled receptors (GPCRs), which typically respond to a stimulus in a cell’s environment by engaging with G ...