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When prioritizing hits from a high-throughput experiment, it is important to correct for random events that falsely appear significant. How is this done and what methods should be used?

Genes that affect multiple, apparently unrelated, phenotypes are thus called pleiotropic genes (Figure 1). Pleiotropy should not be confused with polygenic traits, in which multiple genes converge ...

A patent grants property rights to the inventor of a process, design, or invention for a set time in exchange for a comprehensive disclosure of the invention.

A simple sequential Bonferroni-type procedure is proved to control the false discovery rate for independent test statistics, and a simulation study shows that the gain in power is substantial. The use ...

A bicameral system refers to a government with two legislative houses or chambers.