This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...

Intracellular lipid chaperones dictate the destiny of lipids. Also known as fatty acid-binding proteins (FABPs), these are a group of proteins that coordinate lipid trafficking and signalling in ...

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Both Wnt and BMP signaling regulate maintenance of Lgr5 + intestinal stem cells, but their interplay remains incompletely understood. This study shows that the BMP-suppressed chromatin regulator ...

In two independent hospital systems, past heparin use was associated with a one-year delay in AD onset. It may block ApoE and tau from binding to endogenous heparin-like molecules. For the new study, ...

Proteins that bind to HSPGs may accumulate in the brain ... but researchers speculate it could delay Alzheimer’s by disrupting ApoE-HSPG interactions. In this new study, researchers analyzed ...

Holand og Setskog Sparebank operates as a savings bank. It offers a range of financial services including loans, savings, advice, insurance and pensions to personal and corporate customers. The Bank ...

Secreted signaling proteins of the Epidermal Growth Factor (EGF), Fibroblast Growth Factor (FGF), Hedgehog (Hh), Notch, Transforming Growth Factor β (TGF-β)/Bone Morphogenetic Protein (BMP), and ...