The Hedgehog (Hh) pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. The first and often genetically ...

Figure 1: The Sonic hedgehog (Shh) signaling cascade is important in ... “The search is really on for additional ways to target the pathway.” Several groups have made progress in finding ...

Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems ...

Shadow the Hedgehog is one of the most well-loved characters in Sega's iconic Sonic franchise ... it creates a pathway named the "Miracle of Love." To many, this could strongly hint at the ...